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KMID : 0882420060700010101
Korean Journal of Medicine
2006 Volume.70 No. 1 p.101 ~ p.106
A case of Hashimoto`s thyroiditis with chronic Lymphocytic Leukemia
°­¸í¼ö/Kang MS
À̼øÀÏ/±èµ¿¿ì/±èÈñÁø/Á¤Çö°æ/À¯µ¿¼ö/°íÀçÇâ/Lee SI/Kim DW/Kim HJ/Chung HK/Yoo DS/Go JH
Abstract
Hashimoto¡¯s thyroiditis is an autoimmune thyroid disease characterized by a gradual enlargement of the thyroid gland, extensive lymphocytic infiltration and fibrosis of thyroid follicles. Hashimoto¡¯s thyroiditis occurs frequently in conjunction with a wide range of organ-specific and systemic autoimmune diseases. The association of chronic lymphocytic leukemia with other autoimmune diseases also has been recognized. Here, we report a case of chronic lymphocytic leukemia diagnosed by abrupt painful swelling of the thyroid gland in a 69-year-old woman with Hashimoto¡¯s thyroiditis. The painful enlargement of goiter and elevated levels of antibodies to thyroglobulin were improved after chemotherapy with cyclophosphamide, vicristine and prednisolone.
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